Genomic Medicine: Principles and Practice

Front cover:Genomic Medicine: Principles and Practice
By Charis Eng, Dhavendra Kumar
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Pages: 852
ISBN: 9780199896028
Edition: 2nd edition
SKU: ELB1115420
  • Written by a team of international experts in different aspects of genetics and genomics related to wide ranging medical and health practices
  • Fills the current gap in education and training for the rapidly changing field of applied genomics for diagnostic and therapeutic uses
  • Includes a carefully compiled glossary relevant to genetic and genomic medicine

New to this Edition:

  • New chapters in first section on bioinformatics, proteomics, microbial genomics and genomic education
  • Second section includes new clinically-oriented chapters, highlighting genomic applications (array comparative genomic hybridization, exome sequencing and next generation sequencing) in clinical diagnosis of congenital developmental malformations, Mendelian genetic disorders, and complex cardiovascular, neuro-psychiatric, ophthalmic, dermatologic, inflammatory and pediatric disorders
  • New developments in gene/cell-based somatic therapy, regenerative medicine, and targeted molecular therapy are discussed

Part I: Principles of Genomic Medicine

  • Genes, genetics and human genomics
  • The human genome- structure and organization
  • Human Proteomics
  • Epigenetics, Epigenomics and Human Disease
  • Genes, genome and developmental malformations- Dhavendra Kumar
  • Bioinformatics, Systems Biology and Systems Medicine
  • Pharmacogenomics - Critical Component of Genomic Medicine
  • New Drug Development, Drug Response, and Precision Medicines
  • Mitochondrial genetics and genomics in clinical medicine
  • Genomics Technology in Clinical Diagnostics
  • Microbial Genomics: targeted antimicrobial therapy and genome vaccines
  • Nutritional genomics
  • Genomics in Public and Population Health
  • Genetic testing and genomic screening
  • Biobanking for genomics-based translational medicine
  • Genetics and Genomics Education: The Path from Helix to Health
  • Ethical, Legal and Social Issues in Clinical Genomics
  • The regulation of human genomics research

Part II: Genomics in Clinical Practice

  • Genetic and genomic approaches to clinical medicine
  • Genetic and genomic taxonomy of human diseas
  • Genomics of complex cardiovascular disease
  • Genomics of type 2 diabetes mellitus and obesity
  • Genetics and genomics of osteoporosis and related disorders
  • Genetics and Genomics of chronic kidney disease
  • Genetics and genomics in clinical hematology I- Hemostasis and Thrombosis
  • Genetics and genomics in clinical hematology II- Inherited disorders of haemoglobin
  • Genetics and genomics in clinical hematology III- Acute leukemias
  • Genetics and Genomics of Chronic Inflammatory disorders I: Inflammatory Bowel Disease
  • Genetics and Genomics of Chronic Inflammatory disorders II: Rheumatoid Arthritis and Related Arthropathies
  • Genetics and Genomics of Chronic Inflammatory disorders III: Bronchial asthma
  • Genetics and genomics of neuro-psychiatric diseases I: Seizure disorders
  • Genetics and genomics of neuro-psychiatric diseases II: Multiple Sclerosis
  • Genetics and genomics of neuro-psychiatric diseases III: The Common Dementias
  • Genetics and genomics of neuro-psychiatric diseases IV: Schizophrenia and Bipolar Disorder 
  • Genetics and genomics of neuro-psychiatric diseases V: Learning and behavioural disorders
  • Clinical Cancer Genomics
  • Genomics and Infectious diseases: Susceptibility, resistance and anti-microbial therapy
  • Genomic perspectives of clinical immunology
  • Genomic applications in Clinical Pediatrics
  • Genetics and Genomics in clinical ophthalmology I: The spectrum of genetic eye disease
  • Genetics and Genomics in clinical ophthalmology II: Glaucoma
  • Genetics and Genomics in clinical ophthalmology III: Age-Related Macular Degeneration
  • Genomic applications in audiological medicine
  • Genetics and Genomics of skin diseases I: Diseases of the epidermis: eczema, psoriasis
  • Genetics and Genomics of skin diseases II: Genomics of pigmentation and skin cancer
  • The genetic and genomic practice of reproductive medicine
  • Stem cell Genomics
  • Genomic applications in critical care medicine
  • Targeted molecular therapy
  • Glossary for genetic and genomic medicine- terms, definitions and phrases

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